Analysis, Biological Data It uses mutant DNA polymerase enzymes in nucleic acid sequencing reactions, which is particularly important for sequencing-by-synthesis. A technician uses an Illumina Inc. DNA sequencing machine at the Li Ka Shing Institute of Health Sciences at the Chinese University of Hong Kong in Hong Kong, China, on June 20, 2017. Some of them are essential, while others help us to improve this website and your experience. Illuminas shares dropped sharply following the verdict but have rebounded somewhat since. Opponents included strawmen as well as Qiagen, a Germany-based provider of DNA sequencing technology. personalising content and ads, providing social media features and to Blake Brittain reports on intellectual property law, including patents, trademarks, copyrights and trade secrets. According to Illumina, the '444 patent was set to expire in June 2023 and US Patent No. CH Kilger (Berlin): Christian Kilger, Strawman Some was asking on Twitter about the effect of Illuminas IP expiring on the sequencing industry. Illumina makes ~10x on consumables. 10,480,025, titled "Labelled nucleotides"while . The above analysis relies on the fact that the COGS of competitors is probably going to be similar to Illumina. Saves the visitors preferences selected in the Cookie Box of Borlabs Cookie. Some of them are essential, while others help us to improve this website and your experience. cookies The purchase of this product does not convey a license under any claims in the foregoing patents or patent applications direct to producing the product. PLEASE NOTE: A verification email will be sent to your address before you can access your trial. Each company sought a reasonable royalty for the alleged infringement of its patents by certain features of the accused products. Illumina said in a statement that it disagrees with the verdict, handed down May 6, and intends to appeal, though no action has been taken at this time. Notice is hereby provided under 35 U.S.C. So one option they have is to push pricing as low as they can and have slightly better data quality (lets say, maxing out read length at 300bp as opposed to competitors being at ~100bp and having 90% >Q30 versus say 70%). Simmons + Simmons LLP. As a global company that places high value on collaborative interactions, rapid delivery of solutions, and providing the highest level of quality, we strive to meet this challenge. User-provided information. New Study: China Overtakes US In Competition For Key Emerging Tech, Mexico Issues Highest-Ever Gun-Jumping Penalty. Great! Back in November, a federal jury ruled that four of Illumina's five patents in the California case were valid, awarding it $8 million, according to a Law360 report. But it will be short lived. BGI Group is the corporate parent of both MGI, Complete Genomics owner, and of BGI Genomics. The European patent attorney also regularly files patents for the US company at theEPO. Refuse. For specific trademark information, see www.illumina.com/company/legal.html. If you are under 16 and wish to give consent to optional services, you must ask your legal guardians for permission. The purchase of this product from Illumina, Inc., its affiliates, or its authorized resellers and distributors conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product by the buyer (whether the buyer is an academic or for-profit entity). N choose K, with T targets. Illumina previously won $8 million from BGI in a jury verdict in San Francisco and a ban on U.S. sales of some BGI products. Illumina's shares dropped sharply following the verdict but have rebounded somewhat since. | Interpretation, Certificates (CofC, CofA) and Master Lot Sheets, AmpliSeq for Illumina Cancer Hotspot Panel v2, AmpliSeq for Illumina Comprehensive Cancer Panel, Breast Cancer Target Identification with High-Throughput NGS, The Complex World of Pan-Cancer Biomarkers, Microbiome Studies Help Refine Drug Discovery, Identifying Multidrug-Resistant Tuberculosis Strains, Investigating the Mysterious World of Microbes, IDbyDNA Partnership on NGS Infectious Disease Solutions, Infinium iSelect Custom Genotyping BeadChips, 2020 Agricultural Greater Good Grant Winner, 2019 Agricultural Greater Good Grant Winner, Gene Target Identification & Pathway Analysis, TruSeq Methyl Capture EPIC Library Prep Kit, Genetic Contributions of Cognitive Control, Challenges and Potential of NGS in Oncology Testing, Partnerships Catalyze Patient Access to Genomic Testing, Patients with Challenging Cancers to Benefit from Sequencing, NIPT vs Traditional Aneuploidy Screening Methods, SNP Array Identifies Inherited Genetic Disorder Contributing to IVF Failures, NIPT Delivers Sigh of Relief to Expectant Mother, Education is Key to Noninvasive Prenatal Testing, Study Takes a Look at Fetal Chromosomal Abnormalities, Rare Disease Variants in Infants with Undiagnosed Disease, A Genetic Data Matchmaking Service for Researchers, Using NGS to Study Rare Undiagnosed Genetic Disease, Progress for Patients with Rare and Undiagnosed Genetic Diseases. "BGI has brazenly copied Illumina's proprietary sequencing chemistry. If you disable this cookie, we will not be able to save your preferences. Some of them are essential, while others help us to improve this website and your experience. Illumina Pays To Settle Years-Long Patent Battles, Investors Withdraw $6B From Binance Amid Crypto Regulation, Meta Offers New Options For Researchers Working In Artificial Intelligence, Microsoft, Activision Deal Review Extended By The European Commission, Microsoft Drastically Scales Back Metaverse Project, Focuses On AI, Bill That Aims To Block TikTok Approved By US House Panel, EU: Google promotes rivals to stave off antitrust action. 10,480,025 (the '025 Patent) asserted against BGI in the suit, which are directed to blocked It is Illumina's policy to seek patent protection in the United States and abroad for such technology and products. The latest of these patents is due to expire in 2024. Standard Digital includes access to a wealth of global news, analysis and expert opinion. And I suspect is why theyre shopping around for acquisitions. Except Illumina dont make much money that way. Cookie by Google used to control advanced script and event handling. IP addresses), for example for personalized ads and content or ad and content measurement. How the biggest companies plan mass lay-offs, The benefits of revealing neurodiversity in the workplace, Tim Peake: I do not see us having a problem getting to Mars, Our ski trip made me question my life choices, Michelle Yeoh: Finally we are being seen, Apocalypse then: lessons from history in tackling climate shocks, How Glasgows tiny, muckraking crime mag stays afloat, Smart data to help spot risk and opportunity, Lex, our agenda-setting business commentary (Premium only), Due Diligence, an exclusive M&A newsletter (Premium only). The listed products and their use are the subject of US Patent Nos. Illumina MiSeq Dx Cystic Fibrosis Assays, TruSeq Stranded total RNA Sample Prep Kits, BaseSpace Cohort Analyzer Related Products, BaseSpace Variant Interpreter Related Products, BaseSpace Correlation Engine Related Products. According to an exhibitfiled with the complaint, Illumina said a BioRxivpreprintposted Feb. 20 proved CoolMPS technology infringed the '973 patent. Content from video platforms and social media platforms is blocked by default. My name is Nava Whiteford. Illumina has won a patent infringement suit in the UK against defendant MGI over DNA sequencing technology. Simply log into Settings & Account and select "Cancel" on the right-hand side. Illumina's stock was down more than 14% Friday following the verdict. As part of the deal, each party will drop any challenges to the California and Delaware jury decisions, and Illumina gets a license to the family of patents that BGI asserted in Delaware. Cookie by Google used for website analytics. Invoking principles set out regarding sufficiency, the High Court contended that MGI infringed four of five of Illumina's valid patents. Mathys & Squire (London): Philippa Griffin, Strawman Hoffmann Eitle (Munich): Leo Polz. Illumina innovative sequencing and array technologies are fueling groundbreaking advancements in life science research, translational and consumer genomics, and molecular diagnostics. In the Delaware case, San Jose, California-based Complete Genomics Inc, a BGI subsidiary, had challenged Illumina's "two-channel" sequencing systems and kits to prepare DNA fragments for sequencing of violating its patent rights. We use cookies on our website. Illumina is forking over the $325 million to settle claims following two recent jury decisions in Delaware and California, as well as an antitrust case in California, according to a statement on Thursday from MGI Tech, a BGI affiliate. As of right now, it seems that Illuminas original cluster generation IP has expired (from Manteia) has expired. But in May, a Delaware jury decided that Illumina owes Complete Genomics more than $333 million for infringing on two patents, court documents state. Analysts say the bad news is prompting investors to question the company's strategy of buying Grail, which Illumina forecasts will generate an operating loss of $670mn in 2023 on revenues of. We do not anticipate that this decision will affect our ability to supply and service our customers.. The nearly $1 million Novaseq 6000 is expected to one day unlock the $100 genome. We use cookies on our website. I have equity in a few sequencing companies based on my previous employment (I try to be unbiased in my posts). Law360 takes your privacy seriously. The latter represented Qiagen in one of the proceedings. It also bars U.S. sales of StandardMPS products through Jan. 21, 2023. The companies have been embroiled in a global legal battle over their respective sequencing technologies, with court cases in countries including Germany, Denmark, Switzerland, and Turkey. A spokesperson for MGI Tech Co., which owns Complete Genomics, said MGI is pleased with verdict. You can find more information about the use of your data in our privacy policy. On November 30, 2021, a jury in the patent infringement suits between Illumina, Inc. and BGI Genomics Co. in the U.S. District Court for the Northern District of California returned a verdict invalidating certain patent claims of Illumina's U.S. Patent No. The listed products and their use are the subject of US Patent Nos. other approaches on the market or in development. Hide Cookie Information. The two patents cover technology fornext generation sequencing and were revoked due to formal errors. 287 (a) for the following products: Last Updated: 2022-06-23 Gene sequence giant Illumina is weighing its next moves after a federal jury in Delaware found the San Diego company infringed on two patents from a rival genomics company and awarded $334 million in damages. In addition, although Complete Genomics may seek an injunction, we do not believe there is a reasonable basis for the court to grant one, said Illumina in the filing. _hjClosedSurveyInvites, _hjDonePolls, _hjMinimizedPolls, _hjDoneTestersWidgets, _hjIncludedInSample, _hjShownFeedbackMessage, _hjid, _hjRecordingLastActivity, hjTLDTest, _hjUserAttributesHash, _hjCachedUserAttributes, _hjLocalStorageTest, _hjptid, Meta Platforms Ireland Limited, 4 Grand Canal Square, Dublin 2, Ireland, Openstreetmap Foundation, St Johns Innovation Centre, Cowley Road, Cambridge CB4 0WS, United Kingdom, _osm_location, _osm_session, _osm_totp_token, _osm_welcome, _pk_id., _pk_ref., _pk_ses., qos_token, Twitter International Company, One Cumberland Place, Fenian Street, Dublin 2, D02 AX07, Ireland, __widgetsettings, local_storage_support_test, Vimeo Inc., 555 West 18th Street, New York, New York 10011, USA. Navigating the New Matchmaker Economy David S. Evans at George Washington U. ), Create custom alerts for specific article and case topics and, I took a free trial but didn't get a verification email. Some of them are essential, while others help us to improve this website and your experience. qPCR dominates here because the COGS for qPCR is essentially $1 and the COGS or instruments a few hundred. If its appeal is unsuccessful, Illumina could be required to pay an ongoing royalty until the patents expire in 2029, the company said in a filing with the U.S. Securities and Exchange Commission. "," m.t`2L*] Xl2$cb8PQF =
(Reuters) - Illumina Inc and BGI Group's MGI Tech Co and Complete Genomics have settled U.S. litigation over their rival DNA-sequencing technology, the companies said Thursday. 249 0 obj
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See here for a complete list of exchanges and delays. It also targeted Illuminas library preparation kits and cluster generation and sequencing kits compatible with one or more of the systems, according to court papers. Scripts to download SARS-CoV-2 replacements, Sony CCD-V8AF Video Camera Recorder Viewfinder CRT Notes, Playing with a Handycam CCD-F340 Viewfinder CRT Notes, Thoughts on a new approach to viral testing, Quick script to download Uniprot info for proteins from Pfam trees (Newick tree format), Notes on fixing a broken Gentoo grub install, Notes on using a ILX511 Linear CCD, AD9225 ADC, ICE40HX8K and Nmigen, Thoughts on interviewing with YC as a science based startup, 2018 DNA Sequencing Raises and Acquisitions. No one on our HOA board has been elected and they all remain on by default year after year. The company also filed an anticompetitive suit against Illumina in Delaware last year. Reuters, the news and media division of Thomson Reuters, is the worlds largest multimedia news provider, reaching billions of people worldwide every day. From Europe. df-mp Drries Frank-Molnia & Pohlman Patentanwlte Rechtsanwlte PartG mbB, filed apatent infringement counterclaim against Illumina, https://policies.google.com/privacy?hl=en, https://www.hotjar.com/legal/policies/privacy/, https://www.facebook.com/privacy/explanation, https://policies.google.com/privacy?hl=en&gl=en, https://wiki.osmfoundation.org/wiki/Privacy_Policy. Reuters provides business, financial, national and international news to professionals via desktop terminals, the world's media organizations, industry events and directly to consumers. Illumina has sought to stay ahead by expanding its portfolio of sequencers. Illumina, or (ii) any expiration date or the end of the shelf-life pre-printed on the consumable, but in either event, no later than 12 months from the date of shipment. An Encoding And Correction Approach for DNA Data Storage, Using an SBS-like approach to selectively amplify, Reprogramming a ATTINY85 to use an external oscillator using the Arduino IDE, Nanopore DNA Sequencing Research Groups (August 2018), DNA Sequencing Companies (Updated May 2020), Inheco Control 96 + CPAC Ultraflat Notes (TEC/Peltier), Veeco/Bruker AFM (nanosope) head teardown pics, uMD1 ChipKIT 32 HP Interferometer Interface, Penrose Puzzle Lessons Learned from Rev 0, Embedding Electronics in Transparent Resin, Another iPhone MEMS Mic (different configuration+layers), Throwing the BME280 Combined Pressure/Humidity Sensor in a SEM, MXq Quad Core Android Thoughts (and console kernel messages), 11inch Celestron CPC Series Telescope Repair Initial Photos, A Brief Computational Analysis of Pen-Pineapple Apple-pen, esp32 USB Stick (esp32 + ch340g + buck conv + sd card), FG-100 Soldering Iron Tip Temperature Sensor, Fiddling with a cheap 5 port dumb switch to add VLANs/port mirroring, Marking intervals in gnuplot graph (with shading), awk print text between 2 identical markers in a file, A git pre-commit hook to do SVN style $Date$ substitution, Sony WPSD5 Surround Sound System repair Notes, Interfacing Hitachi HD44780 LCDs using I2C on an Arduino, Notes on Genias new paper nanopore SBS, Are you sure this isnt horse? Marketing cookies are used by third-party advertisers or publishers to display personalized ads. Some of them are essential, while others help us to improve this website and your experience. Hotjar is an user behavior analytic tool by Hotjar Ltd.. We use Hotjar to understand how users interact with our website. This is the first time the UK patent courts have truly grappled with sufficiency at a lower instance. Opponents included strawmen as well as Qiagen, a Germany-based provider of DNA sequencing technology. [1/2]A new office building housing genetic research company Illumina is shown in San Diego, California, U.S., May 30, 2018. Tesla recalls 3,470 Model Y vehicles over loose bolts, Exclusive: Nvidia's plans for sales to Huawei imperiled if U.S. tightens Huawei curbs-draft, Reporting by Blake Brittain in Washington; additional reporting by Raghavi Kasa; Editing by David Gregorio and Diane Craft, Mexico can't match U.S. incentives for proposed Tesla battery plant, minister says, Taiwan's TSMC to recruit 6,000 engineers in 2023, Twitter's revenue, adjusted earnings drop about 40% in December - WSJ, Exclusive news, data and analytics for financial market professionals. Host: https://www.illumina.com | or These two patents appear to be the fundamental IP required to build an Illumina-style DNA sequencer. In a later Delaware case, Complete Genomics accused Illumina of infringing on its own patents with two-channel sequencing systems, kits to prepare DNA fragments for sequencing and kits to immobilize, amplify and sequence fragments. The BGI unit said Illuminas customers infringe the patent, which Bloomberg Law estimates will expire in January 2029, when they use certain systems in combination with its recommended sample preparation and sequencing kits. Show Cookie Information Hotjar Ltd., Dragonara Business Centre, 5th Floor, Dragonara Road, Paceville St Julian's STJ 3141 Malta. Illumina Inc. owes BGI Group, the worlds largest maker of commercial genetic sequencers, $333.8 million after a federal jury in Delaware found Friday that some of its DNA sequencing systems infringe two patents related to technology that deduces each nucleotides identity from two signals. They do this by tracking visitors across websites. You can find more information about the use of your data in our privacy policy. Reach him at blake.brittain@thomsonreuters.com. Griffins clients include New England Biolabs and the Ecole Polytechnique Fdrale De Lausanne (EPFL). endstream
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<. So if youd be interest in investing in (or codeveloping) such a platform, get in touch. It helps push throughout, reduce error rates, and increase read length. Cookie Details The DNA sequencing patents are interesting for competitors such as MGI and the BGI Group, which are also in the . offers FT membership to read for free. 7,566,537 and 9,410,200. 7,771,973, also titled "Modified nucleotides," will expire in August 2022. Want more news? Whats your favorite San Diego County beach? You may also opt to downgrade to Standard Digital, a robust journalistic offering that fulfils many users needs. Browse an unrivalled portfolio of real-time and historical market data and insights from worldwide sources and experts. The reversible terminator IP has not theyre currently using this IP to block the sale of some MGI instruments. David Bilsker, a lawyer from Quinn Emanuel Urquhart & Sullivan LLP who represented Complete Genomics, said the jurys findings shows the strength of Rade Drmanacs inventions. ), NPN Common Collector, Colpitts oscillator notes, NPN BJT Common emitter inverting amplifier, Simple example of SDL in Emscripten (generating graphics from C), Phase Shift Oscillator High Pass configuration, Astable multivibrator oscillator and a little oscillator history, Driving a tiny stepper on an Arduino (without a driver! Password (at least 8 characters required). But they probably wont be the only player to take this approach. 6 February 2023 Personal data may be processed (e.g. You can still enjoy your subscription until the end of your current billing period. The companies have a history of heated courtroom clashes. In late March, a federal judge in San Francisco upheld a jurys November verdict awarding Illumina $8 million for BGI Genomics infringement of at least one valid claim in three of the five genetic-sequencing patents at issue. (This story corrects statement in paragraph 1 that Complete Genomics is a subsidiary of BGI Genomics to reflect that it is part of BGI Group). This latest settlement should put an end to the storm of lawsuits at least for a while. Illumina invented its 2-channel technology before the BGI patents, and BGI was unable to make 2-channel chemistry work until it copied Illuminas technology, the spokesperson said in a statement. The reversible terminator IP has not they're currently using this IP to block the sale of some MGI instruments. The patents in that case expire in August 2022 and January 2023. and other data for a number of reasons, such as keeping FT Sites reliable and secure, See here for a complete list of exchanges and delays. The European Patent Office has destroyed several patents belonging to Illumina, a US manufacturer of genetic engineering equipment. The listed products and their use are the subject of the following US Patent Nos. SAN DIEGO-- (BUSINESS WIRE)-- Illumina, Inc. (NASDAQ: ILMN) today announced that the High Court of Justice, Chancery Division, Patents Court, issued a judgment in its favor in the patent infringement suit filed against the BGI Companies, MGI Tech Co. Ltd; Latvia MGI SIA; MGI International Sales Co., Ltd; and BGI Complete Genomics Hong Kong Co., At the low end is a $20,000 desktop sequencer that put sequencing within reach of more scientists. For Illumina Ive looked at most of these. The jury, which started deliberating Thursday afternoon, also found that sequencers sold by BGIs Complete Genomics Inc. infringe two of three Illumina patents, but it said all three shouldnt have been issued in the first place, mooting any potential award, according to the verdict issued in the U.S. District Court for the District of Delaware. Retailer Reg: 2019--2018 | We use cookies and other technologies on our website. BGIs suit targeted Illumina systems including the NovaSeq 6000, the NextSeq 500/550/550x and 1000/2000 Series, and the MiniSeq. Accept all Save With these players appearing, with a similar data quality, and a similar error profile, I expect that many users will be able to switch platforms if they want. For cost savings, you can change your plan at any time online in the Settings & Account section. During your trial you will have complete digital access to FT.com with everything in both of our Standard Digital and Premium Digital packages. Del., 19-cv-970), Jury also cancels three patents from Illuminas counterclaims, BGI infringement of two Illumina patents mooted by voiding. The patents in that case expire in August 2022 and January 2023. Theyre iterated over the original IP pretty well and have a number of other advantages over new players specifically: This is all technology was developed for Hiseqs and later instruments. Law360 may contact you in your professional capacity with information about our other products, services and events that we believe may be of interest.Youll be able to update your communication preferences via the unsubscribe link provided within our communications.We take your privacy seriously. My contribution to the increasing entropy, and eventual heat death of the universe. In April, Illumina won an $8 million verdict against BGI from a jury in Northern California federal court, as well as a permanent injunction. He said the company is also pleased that the jury invalidated the cases three Illumina patents. 5,964,443 and 6,437,109, European Patent No 0927258 and related patents and patent application licensed from the Wisconsin Alumni Research Foundation. You may occasionally receive promotional content from the San Diego Union-Tribune. The costs of this technology have fallen sharply in recent years. Illumina is represented by Ashby & Geddes PA and Weil, Gotshal & Manges LLP. Well, for a start I expect it to put downward pressure on Illuminas consumable pricing. Many of the cases have settled, though some remain under appeal. ), Illumina Win Over BGI Upheld as Judge Blocks Gene Sequencers (2), Illumina, BGI Trim Patent Claims as Another Jury Trial Looms, BGI Asks For New Patent Trial After $8 Million Loss to Illumina, BGI Must Pay Illumina $8 Million in Gene-Sequencing Patent Spat, Complete Genomics Inc. v. Illumina Inc. (D. After spending the last 10-plus years in court, Illumina and BGI Group have reached a $325 million settlement to resolve a number of patent and antitrust claims across the US centered around the companies DNA sequencing technology. %PDF-1.5
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The DNA sequencing patents are interesting for competitors such as MGI and the BGI Group, which are also in the midst of patent infringement claims. by The license is limited to Illumina's current technology used for massively parallel sequencing in . Back in November, a federal jury ruled that four of Illuminas five patents in the California case were valid, awarding it $8 million, according to a Law360 report. In particular its been disappointing to see the limited impact of sequencing on SARS-CoV2 diagnostics. and its possible those markets might grow. As always there are niches to play in (base modifications, long reads etc.) The Illumina In-Licensed Patents as of the Effective Date are set forth on Annex II, provided that on and after the Effective Date, the Patents set forth on Annex IV (in-licensed by Sequenom from CUHK) shall be deemed added to Annex II, and Annex IV shall be deemed to no longer include any Patents. We support credit card, debit card and PayPal payments. The Singular platform looks like this to me, probably using alternate nucleotides until 2024 that is if they actually launch before 2024. Judge William H. Orricks March 27 order in the U.S. District Court for the Northern District of California resolved a spate of issues in two suits between the rivals, including by its denial of BGIs bid for a new trial. IP addresses), for example for personalized ads and content or ad and content measurement. Then theyll let other players take the low end of the market and try and keep the high end where margins are higher (and users are willing to pay for slightly better data quality). Get U-T Business in your inbox on Mondays. by You can find out more about which cookies we are using or switch them off in settings. 7,541,444 (the '444 Patent) and U.S. Patent No. In this case, the jury found Illumina willfully infringed on BGI/Complete Genomics patents related to two-channel techniques used in genomics sequencing. If External Media cookies are accepted, access to those contents no longer requires manual consent. You can contact me at: [emailprotected]. 258 0 obj
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& Pipeline Setup, Sequencing Data If you are under 16 and wish to give consent to optional services, you must ask your legal guardians for permission. Click here to login, 2023, Portfolio Media, Inc. | About | Contact Us | Legal Jobs | Advertise with Law360 | Careers at Law360 | Terms | Privacy Policy | Cookie Settings | Help | Site Map, Enter your details below and select your area(s) of interest to stay ahead of the curve and receive Law360's daily newsletters, Email (NOTE: Free email domains not supported). One is estimated to expire in December 2025, another in January 2026the jury found BGIs products infringe those twoand a third in February 2026. %%EOF
Privacy Policy We are using cookies to give you the best experience on our website. As I understand it with that IP alone you could make something that looks very much like a genome analyzer 2. All were invalidated in Fridays verdict. The jury also said Illumina infringed the patents willfully, and that three patents it had accused BGI's Complete Genomics unit of infringing were invalid. The industry leader for online information for tax, accounting and finance professionals. How much does it cost to ship 1cm^2 of silicon? In July 2019, Illumina filed counterclaims alleging certain models of the BGISEQ and MGISEQ genetic sequencing instruments infringe three Illumina patents. Patents. The doctor has been at the forefront of next-generation sequencing, having created the first-generation sequencing method, Bilsker said in a statement. Statistics cookies collect information anonymously. The trial began April 25 and featured competing allegations that each companys DNA sequencing systems infringe the others patents.