Trelegy Ellipta can interact with several other medications. These lists dont include all possible side effects. Its the first FDA-approved medication containing three active drugs that can be used once a day for either COPD or asthma. This can eventually cause vision loss if its not treated. It works by activating adenyl cyclase, which then catalyzes a reaction from adenosine triphosphate (ATP) to cyclic 3,5,adenosine monophosphate (cyclic AMP). Most inhaled steroids have a beneficial effect for 12 hours. Revised 5/2022. There arent any herbs or supplements that have been specifically reported to interact with Trelegy Ellipta. Trelegy Ellipta is a combination medication. The drug isnt meant to be used for sudden breathing problems caused by asthma. fluticasone, an inhaled corticosteroid that lowers inflammation and swelling in the lung airways, vilanterol, a long-acting beta-agonist (LABA) bronchodilator that relaxes the airway muscles to help open airways. Breo comes in a powder. Trelegy Ellipta and Symbicort both contain medications that work in similar ways to treat your COPD. Throw away the inhaler 6 weeks after first removing it from the tray or when the dose counter reads zero, whichever comes first. Do not use Trelegy Ellipta if you have a severe allergy to milk proteins (like lactose). It takes rough 5.5 half-lives for the body to clear most, if not all, of a substance. Trelegy Ellipta contains an ICS, an anticholinergic, and a LABA. Symptoms of thrush include mouth pain or white patches in the mouth. Theres also a video on the manufacturers website that shows you the correct way to take Trelegy Ellipta. The drug should not be used to treat acute bronchospasm associated with either COPD or asthma. It also helps keep the drug from harming the environment. It is used for long-term maintenance treatment of these conditions. It is not known if this medicine is safe and effective in children younger than 18 years of age. Its not known if Trelegy Ellipta is safe to take while breastfeeding. This mild side effect is explained in more detail below in Side effect details.. lower back or side pain. Breo (fluticasone furoate/vilanterol trifenatate), Zara Risoldi Cochrane, Pharm.D., M.S., FASCP, Combivent Respimat (ipratropium/albuterol), COPD lung vs. normal lungs in medical scans, vilanterol, which is a long-acting beta2-agonist (LABA), a bone that breaks more easily than it should, seeing halos or bright colors when looking at lights, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, one strip holds either 100 micrograms (mcg)* or 200 mcg** of fluticasone in each blister, the other strip holds 62.5 mcg of umeclidinium and 25 mcg of vilanterol in each blister, people who took Trelegy Ellipta had 15% fewer flare-ups each year than people who took fluticasone and vilanterol (two of the three drugs in Trelegy Ellipta), people who took Trelegy Ellipta had 25% fewer flare-ups each year than people who took umeclidinium and vilanterol (two of the three drugs in Trelegy Ellipta), 16% of people who took fluticasone and vilanterol, a long-acting beta2-agonist (LABA) and an, asthma symptoms arent well controlled on a long-term asthma medication such as an inhaled corticosteroid ICS), or, asthma is severe enough that it needs to be treated with both an ICS and a long-acting beta2-agonist (LABA) drug. But in Trelegy, its combined with fluticasone, an inhaled corticosteroid (ICS), and umeclidinium, an anticholinergic. Because of these actions, they work together to decrease COPD or asthma symptoms and make it easier for patients to breathe. Antimicrobial drugs are medications that are used to treat infections. For asthma, the recommended dosage of Trelegy is one inhalation (puff) of Trelegy Ellipta once a day. Do not use this medicine if you are allergic to any active ingredients (fluticasone furoate, umeclidinium, vilanterol) or inactive ingredients (lactose monohydrate [contains milk proteins], magnesium stearate). If you have a milk allergy, talk with your doctor about safe treatments for your condition. These lists contain examples of mild side effects that can occur with Trelegy Ellipta, with Symbicort, or with both drugs (when taken individually). Is the ketogenic diet right for autoimmune conditions? The combination of drugs works to control COPD or asthma symptoms over time. To help make sure that you dont miss a dose, try setting a reminder on your phone. Trelegy Ellipta is an option for the treatment of asthma in patients not controlled on inhaled corticosteroids and long-acting beta agonists alone. Compared to Breo (fluticasone furoate / vilanterol) 100/25 mcg, Trelegy Ellipta 100/62.5/25 mcg once daily demonstrated a 110 mL significant improvement in FEV1 over a 24 week period. Its not known to interact with supplements or foods. ; Weakened immune system and increased chance of getting infections Trelegy Ellipta can cause eye problems such as glaucoma, increased eye pressure, cataracts, blurry vision, and other vision changes. The maximum recommended dosage is 1 inhalation of Trelegy Ellipta 200/62.5/25 mcg once daily. A steroid medication's half-life determines how long it circulates in your body. They may suggest other medications. Instead, youll use a rescue inhaler for sudden trouble breathing. Then, take your next dose at your usual time. Avoid storing this medication in areas where it could get damp or wet, such as in bathrooms. In comparison, back pain only occurred in about 1% to 4%* of people who took only fluticasone and vilanterol (two of the three ingredients in Trelegy Ellipta). Trelegy Ellipta is also approved for the once-daily maintenance (long-term) treatment of asthma in adults. Alcohol may also weaken the activity of your immune system, making it easier for you to get an infection. It should be stored in a dry place and kept away from sunlight and heat. And too much cortisol can lead to weight gain. Because it contains three medicines, it may be useful for those on a fixed-dose combination of fluticasone / vilanterol (Breo Ellipta) who need added bronchodilation, or those who are already using Breo Ellipta and Incruse Ellipta (umeclidinium) as 2 separate medicines. sore throat. They may have alternate medications that dont interact with Trelegy Ellipta. This may help decrease your risk of getting oral thrush, which is a fungal infection in your mouth. Trelegy is the name of the medication inside the inhaler. Lung function improvements (change from baseline in trough forced expiratory volume over one second [FEV1] at month 12) were also significant in the study. For patients who do not respond adequately to TRELEGY 200 once daily, re-evaluate and consider other therapeutic regimens and additional therapeutic options. You should use Trelegy Ellipta at the same time each day. As with most drugs, some people can have an allergic reaction after taking Trelegy Ellipta. Your monthly Trelegy Ellipta cost savings if eligible. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre using Trelegy Ellipta. COPD is a long-term disease in which the airways and air sacs inside the lungs become damaged or blocked, leading to difficulty breathing. Like Breo Ellipta (above), the drug Symbicort has uses similar to those of Trelegy Ellipta. The medication is in a powder form that you breathe into your lungs. As with all medications, the cost of Trelegy Ellipta can vary. This list does not contain all drugs that may interact with Trelegy Ellipta. Tell your doctor if you have glaucoma or elevated eye pressure before you start treatment. The three active drugs in Trelegy Ellipta are fluticasone, umeclidinium, and vilanterol. The combination of fluticasone and vilanterol has been studied as well. (This is a measurement of lung function and shows how much air you can breathe out in 1 second.) Trelegy Ellipta may not be right for you if you have certain medical conditions or other factors affecting your health. Best food forward: Are algae the future of sustainable nutrition? If you are in the donut hole coverage phase, your copay could vary between $5-$713. Trelegy Ellipta contains fluticasone, which is an inhaled steroid. In these animal studies, there were no harmful effects on babies whose mothers were given fluticasone or umeclidinium while pregnant. Revision date: October 4, 2022. prednisone, Symbicort, Breo Ellipta, Xopenex, Anoro Ellipta, Atrovent, Dulera, Stiolto Respimat, Nucala. According to GoodRx, if you are in the post-deductible phase, your copay could range between $0-$713. (For more about anticholinergics, see Trelegy Ellipta and other anticholinergic medications right below.). Tell your doctor if you are pregnant, planning a pregnancy, breastfeeding or planning to breastfeed before you start treatment. Note: This list is not all-inclusive and includes only common medications that may interact with Trelegy Ellipta. Steady state occurred within 6 days of daily dosing. In studies, Trelegy has shown a positive effect on breathing tests (FEV1) with the first dose, but it may take several weeks or longer for your overall symptoms to improve in COPD or asthma. Trelegy is only inhaled once per day because the medication effect lasts for at least 24 hours. However, this doesnt mean that Trelegy Ellipta will be present in human breast milk. Common side effects when Trelegy is used for COPD include: upper respiratory tract infection, pneumonia, bronchitis, oral candidiasis (thrush), headache, back pain, joint pain, influenza (flu), sinusitis, sore throat, runny nose, altered taste, constipation, urinary tract infection, diarrhea, gastroenteritis, mouth/throat pain, cough, and voice hoarseness. Trelegy Ellipta comes as an inhaler. Trelegy Ellipta is approved for use in adults ages 18 years and older. Trelegy Ellipta is an inhaled medication thats used for long-term treatment of chronic obstructive pulmonary disease (COPD) and asthma. Results showed a 25% reduction in the annual rate of flare-ups vs. Anoro, and a 15% reduction in the annual rate of flare-ups vs. Breo. I have been on Trelegy for a couple of weeks and other inhalers for 18 years, I was short of breath yesterday after I took a puff of Trelegy, dosage is one puff per day. Certain antidepressant medications can interact with Trelegy Ellipta. This may cause the anti-inflammatory effects that are seen with fluticasone treatment. In clinical trials, 4% to 9%* of people who took Trelegy Ellipta developed headaches. Trelegy Ellipta has been evaluated in the treatment of asthma or COPD in studies ranging from 12- to 52-weeks long. For patients who do not respond adequately to TRELEGY ELLIPTA 100/62.5/25 mcg once daily, increasing the dose to TRELEGY ELLIPTA 200/62.5/25 mcg once daily may provide additional improvement in asthma control. Dont take more than one dose in 24 hours. They can discuss rescue inhaler options with you. frequent urge to urinate. Accessed Oct. 21 at doi:10.1056/NEJMoa1713901, Trelegy Ellipta [Prescribing Information]. Can you take Trelegy and Symbicort together? Theres no human data available to determine if any or all of the ingredients in the medication are safe for use while pregnant. Strength. Its available only as a brand-name medication. stomach flu. Serious side effects from Trelegy Ellipta arent common, but they can occur. Symbicort is also approved to treat asthma in children ages 6 years and older. If you develop back pain from taking Trelegy Ellipta, talk with your doctor. Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. These include: Note: For more information about the potential negative effects of Trelegy Ellipta, see the Trelegy Ellipta side effects section above. Talk to your provider right away if you experience blurry vision, eye discomfort, or other changes in their vision after using Trelegy Ellipta. Steady state occurs within 14 days of daily use. Dont use this medication more than once in 24 hours. Trelegy Ellipta contains three active drug ingredients: fluticasone, umeclidinium, and vilanterol. * To learn . They arent meant to be used for sudden breathing problems caused by COPD. Both Trelegy Ellipta and Breo Ellipta are dry powder inhalers. Dont take more than one dose in 24 hours. How long does Trelegy stay in your system? Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Higher FEV1s show better lung function, while lower FEV1s show poorer lung function. Do not flush. These lists contain examples of serious side effects that can occur with Trelegy Ellipta, with Symbicort, or with both drugs (when taken individually). "Trelegy" is the name of the medication inside the inhaler. You can find an updated list of ingredients at the end of the manufacturers patient information. Even if you dont taste or feel your dose, dont take another dose. One study showed that FEV1 in people who took Trelegy Ellipta was 59 mL higher than it was in people who took fluticasone and vilanterol. COPD is a group of lung conditions that include chronic bronchitis and emphysema, and it can cause wheezing, coughing, and trouble breathing. Trelegy Ellipta is contraindicated for use in people with severe milk protein allergies. Some drugs can prolong (lengthen) a part of your heart rhythm called the QT interval. Last updated on Oct 11, 2022. Last updated on Oct 4, 2022. Trelegy Ellipta is indicated for use in adults with either chronic obstructive pulmonary disease (COPD) or asthma. They can recommend medication to treat the current infection. This can cause you to breathe in too much medication, which may be harmful to you. https://www.drugs.com/newdrugs/fda-approves-trelegy-ellipta-fluticasone-furoate-umeclidinium-vilanterol-asthma-5350.html, https://www.gsk.com/en-gb/media/press-releases/phase-iii-captain-study-of-trelegy-ellipta-in-patients-with-asthma-meets-primary-endpoint/, https://www.gsksource.com/pharma/content/dam/GlaxoSmithKline/US/en/Prescribing_Information/Trelegy/pdf/TRELEGY-ELLIPTA-PI-PIL-IFU.PDF. Brand-name medications usually cost more than generics. Strong cytochrome P450 3A4 inhibitors, like ketoconazole, an antifungal medicine, Monoamine oxidase inhibitors, a class of antidepressants, Anticholinergics, for example, cold or allergy medicines (Benadryl and others), FDA Approves Trelegy Ellipta (fluticasone furoate/umeclidinium/vilanterol) for the Treatment of Asthma. Note: You shouldnt use Trelegy Ellipta to treat sudden breathing problems caused by COPD or asthma. Instead, youll use a rescue inhaler for sudden trouble breathing. Lipson DA, Barnhart F, Brealey N, et al. In the trials, Trelegy Ellipta was compared with two of its three drugs: fluticasone and vilanterol. If you no longer need to take Trelegy Ellipta and have leftover medication, its important to dispose of it safely. Its not approved for use in children. Ask your healthcare provider if you are not sure if this applies to you. Tell them each time you start a new medication. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Trelegy Ellipta and Breo Ellipta are both brand-name drugs. Umeclidinium is minimally orally absorbed. Its used to treat chronic obstructive pulmonary disease (COPD) and asthma. However, you should still check with your doctor or pharmacist before using any of these products while taking Trelegy Ellipta. Its FDA-approved for the long-term maintenance treatment of: However, Trelegy Ellipta isnt approved for use as a rescue inhaler to ease sudden breathing problems caused by either COPD or asthma. Clinical studies with over 2,400 patients evaluated improvement in lung function as measured by the change from baseline in trough forced expiratory volume over one second (FEV1) at 24 weeks of treatment. You can also ask your pharmacist for information on how to dispose of your medication. Here are answers to some frequently asked questions about Trelegy Ellipta. If you have sudden trouble breathing, your doctor will likely want you to use a rescue inhaler such as albuterol (Ventolin HFA, ProAir) or levalbuterol (Xopenex). How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, chronic obstructive pulmonary disease (COPD), forced expiratory volume in 1 second (FEV1), Trelegy Ellipta expiration, storage, and disposal, Professional information for Trelegy Ellipta. Below is a list of medications that can interact with Trelegy Ellipta. Note: Some of the drugs listed here are used off-label to treat these specific conditions. These metabolites are either minimally active or have not yet been studied to determine activity. Examples of examples of drugs that contain an anticholinergic medication include: If youre taking an anticholinergic drug, tell your doctor before you start using Trelegy Ellipta. Other interactions can increase the number of side effects or make them more severe. If youre pregnant or are planning to become pregnant, talk with your doctor before using Trelegy Ellipta. There have been reports of very serious allergic reactions in people with milk protein allergies who took other powder medications with lactose in them. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. What drugs are contained in Trelegy Ellipta? COPD: TRELEGY 100/62.5/25 is for maintenance treatment of patients with chronic obstructive pulmonary disease (COPD). Common medications that may interact with Trelegy Ellipta include: Always tell your doctor and pharmacist about all the medicines you take, including prescription medicines, over-the-counter drugs, vitamins, and herbal dietary supplements. Therefore, these medications can cause some similar and some different side effects. Your doctor will determine the best dosage to fit your needs. In the trials, Trelegy Ellipta was compared with a combination of placebo plus two of its three drugs: fluticasone and vilanterol. Step 1: Prepare a dose Wait to open the cover until you are ready to take your dose. Trelegy is the brand name of the medication inside the inhaler. Brand-name medications usually cost more than generics. Trelegy Ellipta was studied in over 10,000 patients with symptomatic chronic obstructive pulmonary disease (COPD) and a history of prior exacerbations (flare-ups). Youll take one inhalation (puff) of the medication once a day. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It should be taken every day to treat your condition over a long-term period. If youre interested in finding an alternative to Trelegy Ellipta, talk with your doctor. TRELEGY in COPD: data from two 12-week studies and a 52-week long-term study Across two 12-week studies in subjects with COPD, the most commonly reported adverse reactions with 1% incidence and more common than BREO were: Long-term safety data: 52-week study in subjects with COPD This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. How long does it take for Trelegy to work? Trelegy Ellipta contains lactose as a major excipient. Trelegy Ellipta is made of three medications that work to help treat symptoms of asthma. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Lungs with COPD may be enlarged, have visible air pockets, or show other signs of damage in comparison to healthy lungs. Be sure to write the date that you open the inhaler on the label. Fluticasone furoate has a very low oral systemic bioavailability, about 1.3%. Its important to note that Trelegy Ellipta contains a powder form of lactose (a sugar in milk). Medically reviewed by Leigh Ann Anderson, PharmD. Do not use Trelegy Ellipta to treat sudden, severe symptoms of COPD or asthma. The word Ellipta refers to the specific type of dry powder inhaler that contains the drug. What are some alternatives for Trelegy Ellipta? You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. Their recommendation will depend on how severe your asthma is and whether youve used other asthma treatments in the past. It is safe to drink alcohol in moderation if you have COPD and use Trelegy Ellipta. Heres a comparison of how Trelegy Ellipta and Symbicort are alike and different. However, no allergic reactions were reported as a side effect of the drug in clinical trials. Trelegy Ellipta may cause headaches. If you miss your dose of Trelegy, take it as soon as you remember. Symbicort has two active drug ingredients in it: budesonide and formoterol. Some people use this inhaler for asthma. Theres no human data available on whether the active drugs in Trelegy Ellipta pass into breast milk or how the drug may affect a child. However, your doctor will likely want you to have a rescue inhaler in case you have sudden breathing problems. Instead, youll use a rescue inhaler for sudden trouble breathing. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. For more information, see the Trelegy Ellipta for COPD section above. This helps prevent others, including children and pets, from taking the drug by accident. Triple therapy with Trelegy also resulted in a lower rate of hospitalization due to COPD than umeclidiniumvilanterol (Anoro). Blocking these mediators can also decrease inflammation in the airways. We simply charge $49 a month per medication to cover the cost of our services. They may be able to suggest a different treatment. Trelegy was also shown to reduce the annual rate of hospitalizations due to severe flare-ups (34% reduction vs. Anoro and 13% reduction vs. Breo). The drugs work in the following ways to help relieve your COPD symptoms: Trelegy Ellipta should start working after your first dose. The word Ellipta refers to the specific type of dry powder inhaler that contains the drug. Its Cmax occurs about 5 to 15 minutes post-dose. Do NOT take two doses at the same time. Avoid storing this medication in areas where it could get damp or wet, such as in bathrooms, as it is a dry powder inhaler. These inhalers are easy to use and include a dose counter so that you know when to refill your prescription. Call your doctor right away if you have serious side effects. You should take one puff of Trelegy Ellipta once a day at about the same time each day. If you take umeclidinium with another anticholinergic medication, the drugs effects can combine and increase your risk for side effects. They may suggest a medication other than a beta-blocker. They can advise you on the best way to feed your child. In 2018, this use was expanded to include the daily maintenance treatment of airflow obstruction in patients with COPD. Higher FEV1s show better lung function, while lower FEV1s show poorer lung function. Trelegy and Breo are the names of the medications inside the inhalers. Trelegy Ellipta (generic name: fluticasone furoate/umeclidinium/vilanterol) is a once-daily triple drug inhaler approved for long-term use in asthma or chronic obstructive pulmonary disease (COPD) and must be used daily to be effective. Trelegy Ellipta costs significantly more than Symbicort. Accessed Oct, 22, 2020 at https://www.drugs.com/newdrugs/fda-approves-trelegy-ellipta-fluticasone-furoate-umeclidinium-vilanterol-asthma-5350.html. How long steroids for asthma stay in your system depends on the type of drug you are taking. In studies, Trelegy has shown a positive effect on breathing tests (FEV1) with the first dose, but it may take several weeks or longer for your overall symptoms to improve in COPD or asthma. It is not used as a fast-acting rescue inhaler for sudden breathing problems. For more information, see the Trelegy Ellipta for asthma section below. Your doctor knows your medical condition the best and can give you a timeline of your treatment response. The FDA-approved strength for treatment of both COPD and asthma in adults is fluticasone furoate 100 mcg / umeclidinium 62.5 mcg / vilanterol 25mcg. However, babies whose mothers were given vilanterol while pregnant did have birth defects affecting their bones. Combivent Respimat (ipratropium and albuterol) is a prescription drug for chronic obstructive pulmonary disease (COPD). You can prevent thrush from developing by always rinsing your mouth after you take your dose of Trelegy Ellipta. Research Triangle Park, NC: GlaxoSmithKline. Before taking Trelegy Ellipta, talk with your doctor about your health history. This can cause wheezing and fatigue (lack of energy). Asthma: TRELEGY is for maintenance treatment of adults with asthma. If you and your doctor determine that Trelegy Ellipta is safe and effective for you, youll likely take it long term. According to the CDC, chronic obstructive pulmonary disease ( COPD) is surprisingly common. LAMA and LABA medicines are anticholinergic drugs that help to relax the muscles around the airways in the lungs. Based on a survey for secondary outcomes, Trelegy also improved patients health-related quality of life when compared to Breo, which included items such as daily symptoms, daily activities and perceived well-being. The exceptions are Arnuity Ellipta, Asmanex, and Trelegy Ellipa, which last for 24. If youre not sure if youll need to get prior authorization for Trelegy Ellipta, contact your insurance company. Pneumonia (when Trelegy Ellipta is used for COPD): Call your provider if you have a fever, chills, cough with mucus, or shortness of breath; Hypersensitivity reaction or anaphylaxis: Symptoms can include rash, hives, swelling around the lips, tongue, and face, and difficulty breathing, and require emergency medical attention. Trelegy Ellipta can cause mild or serious side effects. If you have sudden trouble breathing, your doctor will likely want you to use a rescue inhaler such as albuterol (Ventolin HFA, ProAir) or levalbuterol (Xopenex). Each person's response to medicine can be different. We're talking about chronic bronchitis and emphysema. * This strength of Trelegy Ellipta is abbreviated as 100/62.5/25 mcg. However, its possible that alcohol may worsen chronic obstructive pulmonary disease (COPD) or asthma symptoms, which Trelegy Ellipta is used to treat. Trelegy Ellipta and Symbicort are both approved to treat COPD and asthma in adults. Trelegy is only inhaled once per day because the medication effect lasts for at least 24 hours. How do I store Trelegy Ellipta? Fluticasone furoate is an inhaled corticosteroid that works by decreasing inflammation, which is a main component of COPD and asthma symptoms. In the bodybuilding, Trenbolone is more commonly used in a form of Tren Acetate. Examples of rescue inhalers include albuterol (Ventolin HFA, ProAir) and levalbuterol (Xopenex). You should try to take your dose of Trelegy Ellipta at the same time each day. The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Common side effects when Trelegy is used for asthma included: common cold symptoms, headache, upper respiratory tract infection, and bronchitis. If the medication has been opened for 6 weeks, even if you havent used all of the doses, its expired and should be disposed of. They can review any possible drug interactions for you. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. If you have headaches that are bothersome to you during your Trelegy Ellipta treatment, talk with your doctor. Medicines that interact with Trelegy Ellipta may either decrease its effect, increase its side effects, or change how other medicines work. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The Trelegy Ellipta patient assistance program can provide your medication for free. Its important to note that Trelegy Ellipta is meant to be used over time to control COPD symptoms. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Learn about side effects, warnings, dosage, and more. Its half-life is 11 hours. Seek emergency medical treatment or call 911 if your breathing problems get worse quickly. Ask your doctor or pharmacist if you do not understand these instructions. (A generic drug is an exact copy of the active drug in a brand-name medication.). Therefore, an overdose isnt likely to occur. For more information about what these drugs do, see the How Trelegy Ellipta works section below. There may be another medication to treat your infection that wont interact with Trelegy Ellipta. Trelegy Ellipta has 3 ingredients whose half-lives are between 11 and 24 hours and will stay in your circulation for up to 5 days after the last dose. Other combination medications that may be used to treat COPD include: Other medications that may be used to treat COPD include: Note: Trelegy Ellipta and the alternative drugs listed here are meant to be used over time to control COPD symptoms. Your insurance plan may require you to get prior authorization before approving coverage for Trelegy Ellipta.
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